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(DAMBE does not work with MAC OS Catalina. I will accelerate my upgrading effort to make a full 64-bit version.)

Please cite:

Xia X. 2018. DAMBE7: New and improved tools for data analysis in molecular biology and evolution. Molecular Biology and Evolution 35:1550–1552.

New: A new function has been added for tip-rooting and ancestor-dating analysis of rapidly evolving viruses such as SARS-CoV-2 where no good outgroup is available for rooting the tree. Can work with huge trees with tens of thousands of leaves. The input is a phylogenetic tree (e.g., from PhyML or RAxML). The function can be accessed by clicking 'Phylogenetics | Root a viral tree with collection date'.

Installation instructions:

(If you have already installed DAMBE on your Mac and just want to update to the new version, simply download this dambe.exe file, right-click your installed DAMBE and choose 'Show Contents'. Copy this downloaded dambe.exe file to replace the old dambe.exe in the c:\program files\dambe folder)

I finally found a simple way to install DAMBE on MAC Sierra/High Sierra.

  1. Download DAMBE7.zip. MAC will automatically unzip it to DAMBE7 in the download directory.
  2. Double-click DAMBE7, then choose Open from the shortcut menu. For MACs with El Capitain, DAMBE7 will run right away. For MACs with Sierra/High Sierra, you may see the following warning.

  3. Click OK and then open Apple menu > System Preferences, click Security & Privacy, then click General:

  4. Click Open Anyway in the dialog above. You will see the final warning:

  5. Click Open. You may be informed that DAMBE7 is not optimized for Mac:

  6. Click OK and DAMBE will run. After this, you can run DAMBE by just double-clicking it.
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